TYPE 2 DIABETES PUTS YOUR HEART AT RISK

Here’s something you should know: Over time, high blood sugar levels can lead to a buildup of plaque in your blood vessels, increasing your chance of future heart problems. In fact, type 2 diabetes DOUBLES YOUR RISK of dying from a cardiovascular (CV) event, like heart attack or stroke. And if you have been diagnosed with a CV event, or a disease of the arteries, you have CV disease—and even higher CV risk. Reducing your chance of CV death starts with understanding your CV risk. Get to the heart of the matter.

Get to the
heart of the matter.

Click the questions below to see the facts for yourself.

Does your type 2 diabetes
come with CV disease?

Type 2 diabetes
and CV disease go hand
in hand, increasing the
chance of a CV event.

In fact, for adults with type 2
diabetes, heart attacks are more
serious and more likely to be fatal.

If you are managing your blood
sugar, is that enough to reduce
your CV risk?

Managing blood sugar is helpful,
but alone it does not significantly
reduce CV risk.

How long have you had
type 2 diabetes?

Heightened CV risk often starts
early—and your risk of heart
disease nearly doubles every 10
years you have type 2 diabetes.


Are you currently taking any CV
medications such as statins,
ACE inhibitors, or beta blockers?

If you have type 2 diabetes, you are
at increased risk for potentially
fatal CV events, even if you
are taking CV medications.

Can type 2 diabetes and
CV disease shorten your life?

For adults over the age of
50, having type 2 diabetes
and cardiovascular disease
shortens life expectancy by an average of

7.8 years for men and 8.4 years for women.

Have you been diagnosed with a
heart attack, stroke, peripheral artery
disease, or coronary artery disease?

If you have a history of heart attack,
stroke, or a narrowing or blockage of
the arteries, you have cardiovascular
disease—the #1 cause of death for
adults with type 2 diabetes.

See something worth sharing?
Don’t keep it to yourself!

For adults with type 2 diabetes and CV disease

THE GOOD NEWS—JARDIANCE CAN HELP

The one and only type 2 diabetes treatment with heart

The one and only type 2 diabetes treatment with heart.

While all type 2 diabetes treatments lower blood sugar, JARDIANCE is the only FDA‑approved type 2 diabetes treatment to go beyond lowering A1C to reduce the
risk of CV death
in adults with type 2 diabetes and CV disease.

Ask your doctor if JARDIANCE can go beyond lowering A1C for you.

Bring this discussion guide to help!

WE PUT JARDIANCE TO THE TEST.

We studied JARDIANCE in a clinical trial of over 7,000 adults with type 2 diabetes and CV disease—for an average of 3 years. The people in the study were already taking common type 2 diabetes medicines and common CV medicines such as statins, beta blockers, diuretics, and ACE inhibitors.

The results? A lifesaving cardiovascular benefit.

WHEN ADDED TO COMMON CV AND TYPE 2 DIABETES
MEDICATIONS, JARDIANCE WAS PROVEN TO:

Significantly lower the risk
of death from CV events

If you’d like to know more, read our press release and ask your doctor if he or she has read about JARDIANCE (empagliflozin) tablets in the American Diabetes Association 2017 Standards of Care.

If you have type 2 diabetes and CV disease

IT’S A GOOD IDEA TO TALK TO YOUR DOCTOR ABOUT JARDIANCE.

Bring this guide to your next appointment to get the conversation rolling.

Call a live Certified Diabetes Educator for FREE

GET YOUR JARDIANCE QUESTIONS ANSWERED.

Learn about JARDIANCE 1‑on‑1 when you join My JARDIANCE Support and start your free 30‑minute phone call with a Certified Diabetes Educator. Plus, you’ll get helpful emails, advice from real patients, and more valuable information sent right to you. Because starting out, everyone can use a little support.

Join My JARDIANCEGet Support

Having trouble with your card?
Just call 1-866-279-8990.1-866-279-8990.

Terms & Conditions:

Terms & Conditions: Eligible patients 18 years or older may pay as little as $0/month with a maximum savings up to $250/monthly prescription. Card valid for 12 consecutive months from activation date. Eligible patients may re-enroll for additional 12 consecutive-month periods by reactivating expired card; benefits not to exceed program expiration on September 30, 2019. If you live in Massachusetts, card expires on the earlier of June 30, 2019, or date AB-rated generic equivalent is available. One card per patient, not transferable, and cannot be combined with any other offer. Program not health insurance. Only valid for commercially insured patients in the 50 United States, DC, and Puerto Rico. Not eligible if prescriptions are paid for in part/full by state or federally funded program(s), like Medicare Part D, Medicaid, Vet. Aff., Dept. of Def., or TRICARE and where prohibited by law. Offer may change at any time, without notice.

Patients 18 years or older taking JARDIANCE medication and enrolled in JARDIANCE patient support are eligible for a free phone session with a Certified Diabetes Educator. Phone session may be up to 30 minutes and is for a one-time use only. One session per patient, not transferable, and cannot be combined with any other offer. Program not health insurance. Offer may change at any time, without notice.

WHAT IS JARDIANCE?

JARDIANCE is a prescription medicine used along with diet and exercise to lower blood sugar in adults with type 2 diabetes.

JARDIANCE is also used to reduce the risk of cardiovascular death in adults with type 2 diabetes who have known cardiovascular disease.

JARDIANCE is not for people with type 1 diabetes or for people with diabetic ketoacidosis (increased ketones in the blood or urine).

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about JARDIANCE?

JARDIANCE can cause serious side effects, including:

  • Dehydration. JARDIANCE can cause some people to have dehydration (the loss of body water and salt). Dehydration may cause you to feel dizzy, faint, light-headed, or weak, especially when you stand up. You may be at a higher risk of dehydration if you: have low blood pressure, take medicines to lower your blood pressure, including water pills (diuretics), are on a low salt diet, have kidney problems, are 65 years of age or older.
  • Ketoacidosis (increased ketones in your blood or urine). Ketoacidosis is a serious condition and may need to be treated in the hospital. Ketoacidosis may lead to death. Ketoacidosis occurs in people with type 1 diabetes and can also occur in people with type 2 diabetes taking JARDIANCE, even if blood sugar is less than 250 mg/dL. Stop taking JARDIANCE and call your doctor right away if you get any of the following symptoms, and if possible, check for ketones in your urine: nausea, vomiting, stomach-area (abdominal) pain, tiredness, or trouble breathing.
  • Serious urinary tract infections. Serious urinary tract infections can occur in people taking JARDIANCE and may lead to hospitalization. Tell your doctor if you have symptoms of a urinary tract infection such as a burning feeling when passing urine, a need to urinate often or right away, pain in the lower part of your stomach or pelvis, or blood in the urine. Sometimes people also may have a fever, back pain, nausea or vomiting.
  • Vaginal yeast infection. Women who take JARDIANCE may get vaginal yeast infections. Talk to your doctor if you experience vaginal odor, white or yellowish vaginal discharge (discharge may be lumpy or look like cottage cheese), and/or vaginal itching.
  • Yeast infection of the penis. Men who take JARDIANCE may get a yeast infection of the skin around the penis, especially uncircumcised males and those with chronic infections. Talk to your doctor if you experience redness, itching or swelling of the penis, rash of the penis, foul smelling discharge from the penis, and/or pain in the skin around the penis.

Who should not take JARDIANCE?

  • Do not take JARDIANCE if you are allergic to empagliflozin or any of the ingredients in JARDIANCE.
  • Symptoms of serious allergic reactions to JARDIANCE may include: skin rash, raised red patches on your skin (hives), swelling of the face, lips, tongue, and throat that may cause difficulty breathing or swallowing. If you have any of these symptoms, stop taking JARDIANCE and contact your doctor or go to the nearest emergency room right away.
  • Do not take JARDIANCE if you have severe kidney problems or are on dialysis.

What should I tell my doctor before using JARDIANCE?

Tell your doctor if you have kidney problems. Your doctor may do blood tests to check your kidneys before and during your treatment with JARDIANCE. Also tell your doctor if you have liver problems; have a history of urinary tract infections or problems with urination; are going to have surgery; are eating less due to illness, surgery, or a change in your diet; have or have had problems with your pancreas, including pancreatitis or surgery on your pancreas; drink alcohol very often, or drink a lot of alcohol in the short term (“binge” drinking); have any other medical conditions; are pregnant or planning to become pregnant. It is unknown if JARDIANCE will harm your unborn baby. Tell your doctor if you are breastfeeding, or plan to breastfeed. It is unknown if JARDIANCE passes into your breast milk.

Tell your doctor about all the medicines you take including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your doctor if you take water pills (diuretics) or medicines that can lower your blood sugar such as insulin.

What are other possible side effects of JARDIANCE?

  • Low blood sugar (hypoglycemia): if you take JARDIANCE with another medicine that can cause low blood sugar, such as sulfonylurea or insulin, your risk of low blood sugar is higher. The dose of your sulfonylurea or insulin may need to be lowered. Symptoms of low blood sugar may include headache, drowsiness, weakness, dizziness, confusion, irritability, hunger, fast heartbeat, sweating, shaking or feeling jittery.
  • Kidney Problems. Sudden kidney injury has happened in people taking JARDIANCE. Talk to your doctor right away if you reduce the amount you eat or drink, or if you lose liquids; for example, from vomiting, diarrhea, or being in the sun too long.
  • Increased fats in your blood (cholesterol).

The most common side effects of JARDIANCE include urinary tract infections and yeast infections in females.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.

For more information, please see Prescribing Information, and Patient Information.

JAR CONS ISI 1.11.17

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WHAT IS JARDIANCE?

JARDIANCE is a prescription medicine used along with diet and exercise to lower blood sugar in adults with type 2 diabetes.

JARDIANCE is also used to reduce the risk of cardiovascular death in adults with type 2 diabetes who have known cardiovascular disease.

JARDIANCE is not for people with type 1 diabetes or for people with diabetic ketoacidosis (increased ketones in the blood or urine).

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about JARDIANCE?

JARDIANCE can cause serious side effects, including:

  • Dehydration. JARDIANCE can cause some people to have dehydration (the loss of body water and salt). Dehydration may cause you to feel dizzy, faint, light-headed, or weak, especially when you stand up. You may be at a higher risk of dehydration if you: have low blood pressure, take medicines to lower your blood pressure, including water pills (diuretics), are on a low salt diet, have kidney problems, are 65 years of age or older.
  • Ketoacidosis (increased ketones in your blood or urine). Ketoacidosis is a serious condition and may need to be treated in the hospital. Ketoacidosis may lead to death. Ketoacidosis occurs in people with type 1 diabetes and can also occur in people with type 2 diabetes taking JARDIANCE, even if blood sugar is less than 250 mg/dL. Stop taking JARDIANCE and call your doctor right away if you get any of the following symptoms, and if possible, check for ketones in your urine: nausea, vomiting, stomach-area (abdominal) pain, tiredness, or trouble breathing.
  • Serious urinary tract infections. Serious urinary tract infections can occur in people taking JARDIANCE and may lead to hospitalization. Tell your doctor if you have symptoms of a urinary tract infection such as a burning feeling when passing urine, a need to urinate often or right away, pain in the lower part of your stomach or pelvis, or blood in the urine. Sometimes people also may have a fever, back pain, nausea or vomiting.
  • Vaginal yeast infection. Women who take JARDIANCE may get vaginal yeast infections. Talk to your doctor if you experience vaginal odor, white or yellowish vaginal discharge (discharge may be lumpy or look like cottage cheese), and/or vaginal itching.
  • Yeast infection of the penis. Men who take JARDIANCE may get a yeast infection of the skin around the penis, especially uncircumcised males and those with chronic infections. Talk to your doctor if you experience redness, itching or swelling of the penis, rash of the penis, foul smelling discharge from the penis, and/or pain in the skin around the penis.

Who should not take JARDIANCE?

  • Do not take JARDIANCE if you are allergic to empagliflozin or any of the ingredients in JARDIANCE.
  • Symptoms of serious allergic reactions to JARDIANCE may include: skin rash, raised red patches on your skin (hives), swelling of the face, lips, tongue, and throat that may cause difficulty breathing or swallowing. If you have any of these symptoms, stop taking JARDIANCE and contact your doctor or go to the nearest emergency room right away.
  • Do not take JARDIANCE if you have severe kidney problems or are on dialysis.

What should I tell my doctor before using JARDIANCE?

Tell your doctor if you have kidney problems. Your doctor may do blood tests to check your kidneys before and during your treatment with JARDIANCE. Also tell your doctor if you have liver problems; have a history of urinary tract infections or problems with urination; are going to have surgery; are eating less due to illness, surgery, or a change in your diet; have or have had problems with your pancreas, including pancreatitis or surgery on your pancreas; drink alcohol very often, or drink a lot of alcohol in the short term (“binge” drinking); have any other medical conditions; are pregnant or planning to become pregnant. It is unknown if JARDIANCE will harm your unborn baby. Tell your doctor if you are breastfeeding, or plan to breastfeed. It is unknown if JARDIANCE passes into your breast milk.

Tell your doctor about all the medicines you take including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your doctor if you take water pills (diuretics) or medicines that can lower your blood sugar such as insulin.

What are other possible side effects of JARDIANCE?

  • Low blood sugar (hypoglycemia): if you take JARDIANCE with another medicine that can cause low blood sugar, such as sulfonylurea or insulin, your risk of low blood sugar is higher. The dose of your sulfonylurea or insulin may need to be lowered. Symptoms of low blood sugar may include headache, drowsiness, weakness, dizziness, confusion, irritability, hunger, fast heartbeat, sweating, shaking or feeling jittery.
  • Kidney Problems. Sudden kidney injury has happened in people taking JARDIANCE. Talk to your doctor right away if you reduce the amount you eat or drink, or if you lose liquids; for example, from vomiting, diarrhea, or being in the sun too long.
  • Increased fats in your blood (cholesterol).

The most common side effects of JARDIANCE include urinary tract infections and yeast infections in females.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.

For more information, please see Prescribing Information, and Patient Information.

JAR CONS ISI 1.11.17